Download Addiction (Oxford Psychiatry Library) by David Nutt, Liam Nestor PDF

By David Nutt, Liam Nestor

A part of the Oxford Psychiatry Library sequence, this pocketbook is a transparent and accomplished evaluate of the mind technology underpinning dependancy and the way this is helping clarify the present and destiny therapeutics for the diversity of addictions, utilizing complete color photographs to augment knowing. Addiction makes a speciality of the character of habit as a mind ailment that features a variety of other behavioural qualities reminiscent of impulsivity and present dependence, and discusses the serious position of kinetic and pharmacological components. The textual content explains how the first pharmacological ambitions of gear of abuse at the moment are understood, the relation to the variable nature of habit to diverse components, and the way this can result in new ways to therapy.

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Additional resources for Addiction (Oxford Psychiatry Library)

Example text

Withdrawal usually refers to physiological symptoms experienced upon the abrupt termination of the substance. The response that follows the stage of drug intoxication differs markedly across drugs and is influenced by the chronicity and frequency of its abuse. For some drugs, such as opiates, alcohol, and sedative hypnotics, drug discontinuation in chronic users can trigger an intense, 50 acute physical withdrawal syndrome. If not properly managed, a severe physical withdrawal syndrome can sometimes be fatal.

They are rewarding, particularly during the initial phases of use, because they induce a conscious experience of pleasure. This pleasure induces ‘liking’. ‘Liking’ is related to activity in discrete hedonic ‘hot spots’ within the reward circuitry of the brain (see Chapter 4). Activity in these ‘hot spots’ has been shown to be increased in animals, together with ‘liking’ reactions, when they are stimulated. Unconscious (or implicit) ‘liking’ reactions to hedonic stimuli are also possible without the conscious feelings of pleasure.

There are two forms of associative learning: classical and operant. In classical conditioning, a neutral stimulus is repeatedly paired with a reflex eliciting stimulus until the neutral stimulus elicits the same reflex response on its own. e. e. reduces discomfort) reinforced. Actions that are reinforced increase the probability that the same action will occur again in the future. Dopamine neurons are activated upon exposure to conditioned stimuli associated with rewards. This suggests that dopamine neurons facilitate associative learning.

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